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Dr. Daryl Gioffre (00:00.046)
How's it going? Sorry, was, it's okay. Let me just see. All right, now I'm trying to find where this is. there it is. I have a million buttons open on my thing. I'm like, wait, where, I was messaging a patient saying I was gonna be a little bit late. I'm like, where's the button?

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Josh Dech - CHN (00:00.116)
That's just life stuff and dog stuff and yeah. You got us?

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Josh Dech - CHN (00:16.894)
You're all right. Looks like we're a little discombobulated today, but we're doing doing great. Now, how do you like to be addressed on a podcast? Darryl, Dr. Darryl.

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Dr. Daryl Gioffre (00:26.28)
yeah, no ego issues, but most people do Dr. Darrell.

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Josh Dech - CHN (00:30.464)
Okay, and how do I pronounce your last name? Wanna make sure I don't butcher that.

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Dr. Daryl Gioffre (00:33.678)
It's Joffrey. Kind of sounds out like it's spelled with a J. I apologize, my voice is a little scratchy. I had a soccer tournament for my son who's 10 this week and I'm the coach and it was a crazy tournament. I'm still recovering but a little local honey and propolis is helping that.

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Josh Dech - CHN (00:35.432)
Joffrey, I was hoping it was, it sounds very fancy.

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Josh Dech - CHN (00:52.5)
You're all right. Hey, that's the good stuff. Don't sweat it. Well, Darrell, I've got your standard document here in front of me, your media sheet. Before I get into this, what's your heart stop today?

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Dr. Daryl Gioffre (01:06.734)
I just, how long do you like to go?

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Josh Dech - CHN (01:11.104)
up to an hour. I've rarely broken that. mean, just I've had people like we've riffed because they had the time it was like we ended up being on for 90 minutes or more, but we had it. But usually it's 45 to an hour.

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Dr. Daryl Gioffre (01:12.3)
Yeah, perp.

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Dr. Daryl Gioffre (01:16.718)
Hmm

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Dr. Daryl Gioffre (01:21.582)
And usually that's what happens with me, we go on that long. So I just texted my patient that I realized was at 130, I asked if we could push her to two. So if we go till like 45, then we're okay. 145?

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Josh Dech - CHN (01:36.948)
Yeah. So right now for you, I got you. You're on Eastern time. Yeah. Yeah, that works. Over in Alberta. Yeah. What about yourself?

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Dr. Daryl Gioffre (01:39.982)
It's 12, 1235, yeah. Where are you located? Oh, very cool. Naples, Florida. Yes. No way. Oh, very nice.

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Josh Dech - CHN (01:49.739)
beautiful. We're going to be out that way in May, but Miami. Yeah. Yeah. Looking forward to it. We love I love it out there. It's warm. I got we got another couple inches of snow last night. So

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Dr. Daryl Gioffre (01:58.061)
Yeah. That is crazy. It's now like I'm from New York City originally and being here for three years, it's like you never know like what month it is because it's always sunny and warm and palm trees. It's crazy. But I love it. Totally does. But I'm

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Josh Dech - CHN (02:13.002)
That's hilarious. I know it's funny how it messes with your sense of time. Well, here's what I want to do with you, Daryl. I'd love to learn about what we're going to be getting into. I mean, I have your standard sheet. Is this what you want to follow as a flow or is it like something that you're really just burning to talk about? So I know after doing a couple hundred interviews myself, this, know going through your sheet can kind of get redundant, but it's also business. You know, you got a message to go through. Is there anything in particular you'd like to focus on today?

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Dr. Daryl Gioffre (02:32.94)
Yeah. Yeah.

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Dr. Daryl Gioffre (02:39.438)
I'm happy to go wherever you want to go, so you don't need to hold back on anything. The gut is kind of the core of what I talk about now after having lost my father to esophageal cancer.

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and myself going through gut issues. So I love talking about it and it's just something that is not looked into. It's like, I just got off of the patient right now who for 25 years has been on the PPI, 25 years. spent thousands, military guys spent thousands and thousands of dollars and still having acid reflux, you know? And the problem is, that no one's doing the right testing. They're not doing the right protocols. They're not doing the right things to get to the root cause. So I think the gut

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Josh Dech - CHN (03:11.904)
Yeah.

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Dr. Daryl Gioffre (03:20.59)
it's becoming more mainstream, really looking to the gut, is the cause where all disease begins, where inflammation begins. So talking about the gut and we can get into some specific symptoms if you want that people have like constipation, bloating, acid reflux, leaky guts, a big thing I talk about. Everybody has leaky gut. Research says 50%, other research says 80%. I do something called live blood cell analysis and my testing with thousands of tests confirm that 100 % of people have leaky gut plus.

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Josh Dech - CHN (03:48.704)
I was gonna say it's 100 % now, there's no way.

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Dr. Daryl Gioffre (03:50.103)
It's a hundred percent, but different degrees, right? So I have a phenomenal leaky gut protocol that can heal up, you know, post-antibiotics, which wipes the gut out for two years. We can heal that in two weeks with this protocol. It's amazing. Involving two simple supplements, bioactive silver hydrosol and aloe vera. So we can go over that. Yeah, so like anything you want to take it to as far as that goes, I'm...

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happy to talk about. You can talk about foods that strengthen gut, foods that weaken gut.

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Josh Dech - CHN (04:23.274)
Well, let's... I...

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Dr. Daryl Gioffre (04:24.526)
the most efficient supplements that, know, I mean, there's so many different things we can.

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Josh Dech - CHN (04:28.352)
Yeah, I think the leaky gut conversation is a cool one to have. It's something I'm like, if you got bloat or you got Crohn's and colitis, you got leaky gut. Like it's a spectrum of how bad it's going to be. Same thing. I'm like, it's a hundred percent of people. I'm with you entirely. I think going down the leaky gut acid reflux route is probably really cool. I did an acid reflux episode on like number eight and I think we're on 165. So why don't we kick off with acid reflux? We'll follow that rabbit hole and see where it takes us.

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Dr. Daryl Gioffre (04:48.78)
Yeah.

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Dr. Daryl Gioffre (04:55.778)
Sounds like a plan.

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Josh Dech - CHN (04:57.204)
Beauty. Any questions for me before you just kick things off and get rolling?

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Dr. Daryl Gioffre (05:00.206)
No, everything sounds okay from, I have an air filter on here. Is that okay? You don't hear the sound, do you?

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Josh Dech - CHN (05:05.296)
Got an editor. I mean that's his job. I do hear it a little bit like is if it's yeah sure if you want

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Dr. Daryl Gioffre (05:07.566)
Let me turn it off. No problem.

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Dr. Daryl Gioffre (05:17.262)
you

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Josh Dech - CHN (05:18.528)
Oh, it is much quieter. Yeah. Yeah, it's a lot better. Yeah, there's no like hissing fan in the background. That'll just make your voice a lot clearer as we as he goes through the editing. It won't be so much denoising. All right, beautiful. Well, I'll kick things off with a quick welcome to record all the intros and post edit and we'll go from there. Dr. Darryl Joffreman, welcome to the show.

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Dr. Daryl Gioffre (05:20.174)
Better? Okay.

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Dr. Daryl Gioffre (05:26.638)
Perfect.

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Dr. Daryl Gioffre (05:33.93)
Awesome.

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Thank you so much, great to see you.

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Josh Dech - CHN (05:40.702)
I'm looking forward to today because it has been over 150 or more episodes since we've talked about some of these topics on the show. So we're overdue and I think you're just the guy to do it. Really quick, we were talking about something off air. What percentage of people have leaky gut?

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Dr. Daryl Gioffre (05:58.947)
Well, there is what the research shows and there's what we're going to tell you today, right? So the research shows that some research says 50%, other research says 80%, but my research was based on years and thousands of live blood cell analysis tests. And then also we do some gut testing through what's called a GI map. It's a DNA stool sample test where we look at something called the zondulin marker, which is a marker for leaky gut confirms that that number is a hundred percent.

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Josh Dech - CHN (06:03.178)
Right, right.

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Dr. Daryl Gioffre (06:24.278)
Now with that, when I say 100 % of people have leaky gut to different degrees, some people it's a small amount, other people who have basically been on multiple rounds of antibiotics, eating a very acidic diet loaded with sugar and grains, gluten-containing grains and other inflammatory foods that promote leaky gut, then it's gonna be higher. But the reality is that 100 % of people have leaky gut. It's a huge problem because Hippocrates said it best, all dis-ease begins in the gut.

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And he was absolutely right. But the problem that most people aren't talking about is that number one, we got to look at the gut and start to figure out like what is going on in the gut that's causing all of this dis-ease, which is a lack of balance, lack of harmony, dysbiosis. The more of that that continues, that leads to disease over time. Because what happens is that you have different forms of toxins and food sensitivities and stealth gut infections that are inside your gut. Everybody's got them. I mean, we're more toxic than we've ever been in human history.

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And here's the thing, your gut is the body's first line of defense. So when we have these cheese holes, and for some people it's like a completely like hydrogen bomb, the completely gut wall is emaciated, things are gonna breach through that barrier and then they enter into the body and that's where the real disease happens because they become systemic, they drive up inflammation and we look at chronic degenerative disease, heart disease, cancer, which is now overtaken heart disease as the number one killer in 21 states.

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Josh Dech - CHN (07:39.84)
Hmm.

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Dr. Daryl Gioffre (07:50.991)
Alzheimer's which parallels inflammation of the brain. It's something that we're dealing with in an epidemic proportion. The question is, like which lane are we gonna go? it, we're doomed, we're doomed. But here's the good thing guys, this is all reversible. You know, just had a patient who I just was on, I was telling you before, 25 years of reflux, spent thousands of dollars, done tons of testing on all this and here he is in a worse place than he's ever been. He's been on PPIs for.

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Josh Dech - CHN (07:56.896)
Mm-hmm.

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Josh Dech - CHN (08:00.256)
So we're all doomed. Cool. Thank you for that. Show's over, guys. That's it.

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Dr. Daryl Gioffre (08:19.662)
25 years. Like when you get that box Josh it says don't do this for more than 14 days. It's crazy. So the reality is that this is something that so many people are dealing with. I dealt with it myself but it is reversible. It is 100 % reversible. You have to get to the root cause and start to uncover the root cause and once you do then your body can heal from this.

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Josh Dech - CHN (08:20.768)
That's wild.

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Josh Dech - CHN (08:26.048)
no.

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Josh Dech - CHN (08:40.416)
Yeah, and I think before we can really understand how to heal from something, I'm a big advocate for understanding what it is and why it works. Now we get the concept of leaky gut. Can you break it down for us? Really? What is it on a very tangible level? So I hear people all the time and I got a Crohn's colitis group of like 14,000 people on Facebook. They're always communicating, asking questions. Someone says, do I have leaky gut? Like, honey, you got Crohn's disease. Your gut is the definition of leak. So I think there's a big misunderstanding of what it actually is.

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Dr. Daryl Gioffre (09:07.202)
Right. Right.

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Josh Dech - CHN (09:10.208)
Break it down for us here, Daryl. What is leaky gut?

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Dr. Daryl Gioffre (09:13.486)
So I like to keep things really simple so people can understand this. So you need to look at your gut like a garden, right? You want lots of flowers, which are the probiotics. The probiotics, they basically help us digest food. They communicate with each other. They help you maintain a proper gut pH. But what they also do is they help defend that gut wall against any irritants that might be trying to breach through that gut wall. So you want that gut microbiome to have lots of flowers. You don't want lots of weeds. And unfortunately for most of us,

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the weeds are overtaking the garden. That term we call dysbiosis. So in other words, leaky gut is when you have these specific stealth infections that could be something like Citrobacter or Pseudomonas or Streptococcus infection, or it could be a parasite. It could be an active virus. It could be a food sensitivity. It could be a toxin like an herbicide, a pesticide, a fungicide, glyphosate, which is a cancer causing chemical, right? So it's a very small list of environmental triggers that can create this.

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So what happens is those are the weeds in our garden. And what happens is, is when those weeds start to become more in number than the probiotics that are defending and reproducing to basically protect that gut wall, you get something called leaky gut. Because what these things do is they basically punch holes through that gut wall, just like Swiss cheese, and they start to go into the bot. It's like you have a bar, right? And you want to have a clean bar and a nice experience there.

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And then all of sudden like all these hooligans come in they take over the balancers they get in they start basically Making ruckus in the barn everything gets messed up. That's what leaky gut is All right You do not have the defense that you once did and the problem is that we're seeing children born with this now because of the Antibiotics given in birth and all that so again everybody has it But the cool thing is that is reversible and as long as we can contain things in the gut Then it's gonna be eliminated out of the gut, but the second they go through that gut wall

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Josh Dech - CHN (10:55.008)
Mm-hmm.

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Dr. Daryl Gioffre (11:08.61)
that can hit the thyroid gland, can cause things like Hashimoto's disease, which is an auto antibody. Your immune system is not attacking itself like so many people believe. It's not the way it works. Your immune system is a lot smarter than that. One day it doesn't decide to go rogue on yourself and say, all right, we're gonna go attack the thyroid gland. No, what happens is that these stealth infections and these toxins that breach through that gut wall, they become systemic and we're only as strong as our weakest link. So they might hit your liver, or they're definitely gonna hit your liver.

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They might hit the thyroid gland. They might hit your brain. And for me, about four years ago when I was dealing with mold toxicity and I had lot of issues with my gut from the mold that I didn't know was in my house when we were living in Newport Beach, California for a couple years, literally it attacked my brain. And my brain became so on fire. It wasn't brain fog. It was what I call brain debilitation.

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Josh Dech - CHN (11:38.792)
Mm-hmm.

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Dr. Daryl Gioffre (11:59.791)
I had done an MRI with NeuroQuant, which measures not only how your brain is looking and functioning and inflammation levels, but is your actual brain atrophying? Is it degenerating? Is it decaying because of these pathogens attacking it? Because pathogens love the brain, albeit mold, Lyme disease, but also these pathogens from the gut that we're talking about. Streptococcus, one of the most common gut infections that leaches through that gut wall, hits the brain within 30 minutes, drives up inflammation, one of the top causes of anxiety and depression.

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Josh Dech - CHN (11:59.841)
Hmm.

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Dr. Daryl Gioffre (12:28.62)
So here's the problem, so many downstream issues that we're seeing in our health from thyroid imbalances, reproductive problems, skin issues, not being able to lose weight, brain issues, cognitive function issues, you have to look at the gut and most doctors aren't doing it.

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Josh Dech - CHN (12:44.352)
Mm hmm. It's amazing how we have this evidence, clear evidence. I mean, back from the 90s, even, we understand that zonulin is a real thing. We understand that leaky gut is a real thing. We understand the mobilization of toxins and how your body will bind cholesterol onto these toxins. So if these toxins get to your brain and they bind cholesterol to neutralize them, well, it turns the plaque and now you got Alzheimer's or Parkinson's does the same thing in your heart. Now you got heart disease. And we have this evidence that we have doctors who are

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downright refusing, it seems, to look at the gut. Why do you think that is?

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Dr. Daryl Gioffre (13:18.468)
it's a phenomenal question. You have to look at the entire allopathic industry. And again, I'm not one to ever beat up the allopathic industry. Well, I do, but like it's, when I say that, you know, this is all they're taught, you know? It's like you get zero nutrition in medical school and you come out and your way of treating a symptom, a pain or whatever they're treating is by giving a drug, right?

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Josh Dech - CHN (13:27.504)
I am.

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Josh Dech - CHN (13:34.814)
Yeah, I agree.

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Dr. Daryl Gioffre (13:44.975)
Um, and here's the big issue with that. We make up 5 % of the world's population. spend over 50 % of the world's money on what they call medical care. I call it sick care because we do not have a healthcare system. We have a sick care system. And the latest research I've read, the number changes a lot is that we rank 72nd in world health. can't even name 71 countries ahead of us, which is crazy. So how on earth are we the most technologically advanced country in this world? Yet we are ranked 72nd.

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We rank dead last amongst all industrialized nations in almost every health category. For the first time in human history, our longevity has lessened. So my children who are seven and 10 have less of a lifespan than we do, which is to me, that's just very, very sad. So we have to look at the industry, what they're taught or what they're not taught. And I hate to say it, the pharmaceutical companies, all these industries are in bed together. They don't want you to be healthy. They want you to be customers to the sick care industry for the rest of your life.

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Josh Dech - CHN (14:26.848)
crazy.

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Josh Dech - CHN (14:38.005)
Yeah.

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Dr. Daryl Gioffre (14:41.592)
You know, that's why you have the FDA, you have the food industry, and I think there's a lot of well-intentioned doctors out there. I really do. But again, just like the patient I just saw, they went to the doctor. He went to eight GI doctors, by the way. I was the ninth. And we're gonna get this guy well, because we did the right testing, we found the root cause, and everything that he's been told to this date, 25 years, was complete contradictory to what he needed. And that's why he's still suffering, that's why he's still on PPIs, and that's why he's getting worse, not better. That's crazy.

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So they're basically being told by the pharmaceutical companies what the treatment parameters should be and they're basing those treatment parameters by the limitations of what the insurance will cover or not cover. It just doesn't work. They're treating symptoms if that, because when you take a PPI, what research of September last year showed and revealed that 54 % of the time, the PPI is not gonna make you feel better. So here I am taking this drug that's one of the worst drugs for your system because now every time I take that pill,

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I have at least 95 % reduction of stomach acid. Why is that bad? Well, what's digesting your food? You're not what you eat, you're what you digest, absorb, and assimilate. So when you eat your food without stomach acid, you cannot get those nutrients into your cells. You could be eating the best strength eating diet, gut balancing diet, with all these foods, could be organic, but if you're not breaking those foods down into a tiny particle that could be brought down into the cell, you're gonna be malnourished, even on healthy diet.

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Number two, you're gonna create food sensitivities. And food sensitivities is not just an unhealthy food. He was saying that he was on a low-fod-mod diet and it's not working. I'm saying because half the foods you're eating, you're actually creating inflammation from. Because we did the right test that's measuring are these foods creating inflammation in your body because you can't digest them. And now the immune system that lives in your gut, and remember, 80 % of the immune system lives in your gut, is gonna attack that food because it thinks that food is non-self. It thinks it's a pathogen.

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Josh Dech - CHN (16:22.485)
Mm-hmm.

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Dr. Daryl Gioffre (16:39.234)
And then the third thing is that the stomach acid is the first line of defense. So without it, you're basically having all these toxins come right through and they kind of get right into the body. So the PPI goal to actually help you with your acid reflux, it might, I say that word might help your symptoms, but it's going to make you so sick and end up killing you down the line because of all the things it's doing to your body. By the way, the cause of reflux is not too much acid. It's too little acid.

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Josh Dech - CHN (17:00.831)
Yeah.

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Dr. Daryl Gioffre (17:06.744)
and that's supported by 16,000 research journal articles. So they're taking the root cause, which is low stomach acid and a massive mineral deficiency, and they're actually making that worse. So it's the paradigm that they kind of, that they live in, and it's not that there's not well-intentioned doctors out there. They just have one tool in their tool bag, and it's drugs, and they don't work. Drugs work for crisis care. Surgery works for crisis care. It's not healthcare. So we need to focus on more self-care.

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Josh Dech - CHN (17:16.511)
Yeah.

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Dr. Daryl Gioffre (17:33.975)
More healthcare, so self care are the things that we do for ourselves that make us healthier. Healthcare are the things that other people do for us that make us healthier. And the more self care we do, the more healthcare we do, the less crisis care we will need. So the goal is to not to ever have to go to that world and live in that world. And unfortunately some people do because they just neglect it for their entire life and now they wait for that toothache to show up and when that toothache shows up, the tooth might be lost already. If you get the analogy.

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Josh Dech - CHN (17:47.583)
Yeah.

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Josh Dech - CHN (18:02.368)
I do. I want to backpedal this a little bit here because you said something that I say often. I love to hear it explained in just a different set of words. The cause of acid reflux is not in fact too much stomach acid. It is too little. And this is something I've talked about for a freaking decade since before I even understood nutrition. I was like, does it make sense? You take the antacids and then most of you will actually still have acid reflux anyways. There's clearly a problem. So back it up for me here.

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Why is low acid the cause for acid reflux?

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Dr. Daryl Gioffre (18:36.94)
And a lot of people with acid reflux right now are like, what? What are they talking about? Like, no. It is contrary to what our common sense would think, right? Because it is the acid that causes all the symptoms. And the symptoms have changed so much. It's not the classic chest burn that most people think of acid reflux. But for me, it was the throat burn. It was every morning having to clear my throat, having to cough. For my dad, I'll remember for years, he had this like dry

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Josh Dech - CHN (18:39.986)
Yeah, excuse you, Daryl.

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Dr. Daryl Gioffre (19:06.71)
in coffin. was like, what is that? Why is that? So again, it is the acid that causes the symptoms. So let's not get that wrong. That is causing the symptoms, but it's low acid that creates all the triggers because we need stomach acid. When I say get off your acid, which is the tagline of my company, I'm not talking about decreasing your stomach acid. That's bad. I'm talking about reducing the acidity in the tissues, the toxic exposure that's causing all that inflammation in the rest of the body. But when we look at the stomach,

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you need sufficient levels of acid. And here's what the research shows. Once we hit age 20, and I think this happens even earlier now, because I'm seeing reflux in teens, which is crazy, we don't get stronger, we get a little weaker, right? We don't get faster, we get a little slower. We don't produce more stomach acid, we produce less. It's just a natural part of aging. And at age 20, what the research shows is every decade, we produce at least 10 % less acid in the stomach. And I think that number is way higher. So what happens is, that,

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you have a valve that goes between your esophagus and your stomach. It's called the esophageal sphincter. And that valve, when you eat food, should basically open up to allow the food to come into the stomach. And what happens is, like, your stomach will make more acid on demand, depending on the food. You eat more animal protein, you need more acid, right? And what happens is, when there's sufficient levels of stomach acid, that valve will close. So what we found in people with acid reflux is they have a weakened valve. So that valve is kind of like stuck.

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It's not kind of open all the way, it's not closed all the way. So even though they have lesser levels of acid that's creating that, when they go and lay down at night, what happens? The acid creeps up into the chest, into the throat, into the sinuses. You'll see patients with like crazy mucus when they wake up in the morning, like not to be gross, but tons of like yellow boogers and bloody snot's coming out, ear pain.

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That's because the acid literally goes all the way up into that area. And what happens, think about what acid is from a common sense standpoint. It's corrosive. It could burn a hole through metal and chicken bone. So it's literally corroding the walls of that tissue that wasn't meant to withstand that low of a pH, that acidic pH. And what happens is your body starts to create an inflammatory response and make mucus in return. And that's where all the symptoms come from. The other thing that happens is that you need the acid to digest your food. So with not enough sufficient levels of stomach acid,

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Josh Dech - CHN (21:02.218)
Mm-hmm.

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Dr. Daryl Gioffre (21:24.578)
When you eat the food, the food gets stuck in transit. It's like a traffic jam. So normally you want that food to move quickly through the digestive system, but it doesn't because it's not digesting. I'm going to say that important line again, guys. You're not what you eat. You're what you digest, absorb, and assimilate. When you have low stomach acid, which happens as we age, which is why we see more acid reflux in people in their 30s, 40s, 50s, 60s in that aging because they have lower levels of stomach acid, when you eat the food and it hits the stomach,

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that food takes longer to digest and now the bacteria is gonna start to ferment that food. You're basically like rusting and rotting and decaying that food before it should get down the line where it needs to go. And here's the other problem is that you have to look at the entire digestive process as like a conveyor belt. And every step needs to happen. Like you need the acid to break down the stomach and then you need enzymes from your pancreas and bile from your gallbladder to further help the assimilation of fat and protein and carbs. If one of those steps has

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has an error in it or it's not functioning properly and again we're at like the top of the chain here with the stomach acid then everything else is going to be messed up downstream.

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Josh Dech - CHN (22:32.832)
Yeah, absolutely. Now, I want to go back again, and we keep backing up on you here. You talk about a weakened sphincter and the idea behind acid reflux that I've always understood and subscribed to is that it's actually a signaling issue. So you have too low of stomach acid in your sphincter is the indoor and outdoor of your stomach require both pH and pressure to be signaled to shut. So they need acidity and they need a large volume of acid like fluid in the stomach to signal and say, Hey, we're going to close up.

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Now, if you're stress chronically, you're not chewing your food properly, whatever it is, you're gonna have this low stomach acid. Therefore, you don't have the signals to close those doors on the stomach. This is what causes the reflux. Now, you talk about a weakened sphincter. Is that a signaling issue due to low acid? Is that overeating and stretching the sphincter? Like what happens to weaken a sphincter that it won't close?

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Dr. Daryl Gioffre (23:05.645)
Yep.

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Dr. Daryl Gioffre (23:11.726)
That's right. Love that.

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Dr. Daryl Gioffre (23:24.588)
It's definitely, I love that analogy by the way, it's definitely a signaling issue is a huge part of it for sure because that valve needs to be signaled when there's sufficient levels of acid to close and over time that's gonna weaken the valve. But the other big thing that we see which is so rampant in our modern acidic standard American diet, sad diet lifestyle is a mineral deficiency, especially magnesium. So the valve is basically, it's like a muscle, right? When you get a muscle knot in your back, what do you do? Well, you press on it.

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So there's specific adjustments, physical adjustments that I teach patients to do that can actually help that sphincter start to function better. But what we do is we put our patients on minerals, trace minerals, macrominerals and magnesium. I magnesium is the fourth most abundant mineral in the body. Yeah, I'm going to tell you it's one of the biggest deficiencies in the Western hemisphere. I mean, it's such a huge, huge deficiency, not just leading to sugar cravings. It's the number one neuro protector of the brain, but also

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massive dysbiosis and acid reflux. every patient that has acid reflux in any sort of gut issue, you know that they have a big mineral and magnesium deficiency that needs to be addressed. And I love what you said about stress, by the way. Stress is, I'm gonna tell you stress outweighs anything you can eat or drink a million times to one in terms of the dysbiosis that it creates inside the gut. Because I always use the analogy when I moved here to Florida.

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Josh Dech - CHN (24:34.176)
So walk me...

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Mmm, huge.

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Dr. Daryl Gioffre (24:50.542)
literally three months after we moved here, hurricane Ian came. It was like the most traumatic and damaging hurricane in Florida history. was awful. And I always say like, when a hurricane comes, you're not going to remodel your kitchen. It's like, you're going to stay, you're going to fight that hurricane, you're going to board up the windows, you're going to run from the hurricanes, you're going get in that car and you're going to flee to someplace safe, or you're going be so scared, you're going to freeze like a deer in headlights, right? And Dr. Joe Dispenza talks about this all the time is that when you're in that fight or flight state,

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You can't go inwards and focus on growth and repair. Everything is projected outwards. Everything. And it's the same exact thing with your body. Your body doesn't care about digesting its food or your immune system when a T-Rex is chasing you down for lunch. It just wants to get you out of danger. But here's the problem. We are literally under significant chronic exposure to not just physical stresses, not just EMF stresses, but emotional stress. We are marinating in our cortisol.

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Josh Dech - CHN (25:33.3)
Mm-hmm.

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Dr. Daryl Gioffre (25:48.235)
And when we have that amount of stress and that amount of fight or flight, mean, 90 % of us are trapped in this vicious cycle of fight or flight, your whole digestive system shuts down. You're not going to digest your food. And when you don't digest your food, the whole chain happens from that point. So managing stress, breathing, chewing your food into a smoothie, those things are so important because the stress, especially, you know, when COVID happened, it was a huge, huge cause for so many gut issues.

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Josh Dech - CHN (26:17.44)
That's an interesting conversation to have in itself. mean, COVID versus gut issues. Is it the virus? Is it the shots? I believe it's a combination of both. We've seen it affect many, many different areas of the immune system with autoimmune disease, gut disease, heart disease, all kinds of issues we've seen it driving. Now that brings me to my next question then, because we have this system now. You chew your food, that stimulation of chewing turns on digestive enzymes, stomach acid, et cetera, et cetera, and then you swallow your food.

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Based on what your body detects in the stomach, it continues to produce more or less stomach acid based on the needs at hand. And then you digest your food and it goes through this assembly line in a timely fashion, bacteria start to take part, and then it comes out as poop. The timeline or the assembly line, as you say, is check, check, check, everything's good to go. But then we have these instances where something in the assembly line gets screwed up. So we have acid reflux due to high stress, due to chewing too quickly, due to mineral deficiencies, you don't have zinc or magnesium.

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So you're not producing acid or your sphincters aren't working, something. And then we jump ahead now and either acid reflux with hyperfermentation of food leads to leaky gut or stress leads to hormones which create leaky gut or a combination of anything creates these bacterial overgrows or fungal overgrows or some kind of infection like the weeds in the garden that then create leaky gut. And so here we are talking about some base causes of leaky gut. Someone's listening going right now. They're like, but I chew my food.

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I'm not under that much stress. actually do a little breath work before I eat. I feel really good, but I'm pretty sure I have leaky gut. What else might be causing leaky gut? Big one I've heard is EMFs. What are your thoughts on some of that?

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Dr. Daryl Gioffre (27:59.183)
Absolutely. mean, I'm wearing an EMF blocker right here. I I have one on my desk. I have one for the house. EMFs are a massive disruptor of cellular health. You know, we have to look at every form of toxin, any form of environmental trigger. So that's the word. You mentioned autoimmune before. Again, it's not the immune system attacking itself. You can have a pre-genetic disposition, which every autoimmune issue has. I mean, I got hit with mold. I have a pre-genetic disposition. It's called SIRS, chronic inflammatory response syndrome, where

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Josh Dech - CHN (28:02.218)
Hahaha.

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Dr. Daryl Gioffre (28:28.812)
I have a 17-2-52 haplotype, HLA haplotype. So if I go into water damage building, I'm done. My immune system can't recognize the mold or the biotoxin, but there's two other components that have to be in place that are going to basically affect if I get taken out by that toxin and mold is just the example here. It could be any gut pathogen or any, any environmental trigger. but what happens is there has to be dysbiosis and a leaky gut. And number three, there has to be the environmental trigger. So the problem

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is the environmental trigger. Cause everybody's got dysbiosis. We said it, everybody's got leaky gut, different degrees, but it's the amount of exposure to the environmental trigger coming into the body. So if you live in 2025, you're going to be under attack. Your gut is under attack 24 seven. It literally is your first line of defense. So again, I mentioned a few things. It's a small list. It's the food sensitivities. It's the toxins, the food toxins. I'm talking about dairy. I'm talking about gluten. You got to go gluten free.

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Gluten causes massive dysbiosis, a massive leaky gut. So again, people that have celiac, which is the actual end stage of gluten intolerance, 1 % of the population, I think the number's way higher, they have the pre-genetic disposition, they have the dysbiosis and the leaky gut, but what happens is the trigger for them is the gluten. So we have to remove the trigger from the diet, or we have to remove the exposure. I had to get out of that house that was giving me the mole. If I could get out of that exposure,

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that biotoxic kept attacking my gut, that's gonna keep attacking the gut wall creating leaky gut. If you don't remove gluten from your diet, that gluten comes in, it's gonna trigger those zondylin markers, you're gonna have leaky gut. If you don't remove that sugar or the bad sugars, ultra processed sugars from the diet, that's gonna trigger leaky gut. And it's not about like this crazy, insane lifestyle where you gotta give everything up, it's not about that, it's not about deprivation, right? It's about just finding your balance, finding your rhythm and knowing what's going on inside your gut that's causing all the damage.

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That's why my mantra is test don't guess. You need to know.

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Josh Dech - CHN (30:27.53)
Well, talk about that. How do we do that? What are we testing? How do you identify your exposures? And is there a way if you're like, you know what, it's really expensive. I don't want to spend a thousand bucks on a total tox test to do urine and hair and stool and whatever. What are our options? How do you test and identify these exposures?

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Dr. Daryl Gioffre (30:44.366)
Yeah, and I wouldn't do all those tests. You don't need to do all those tests, but when it comes to the gut, the two tests that you need to do, which even GI doctors aren't doing, it's an MRT test, which is a mediator release. It's a food sensitivity test. So we're not looking at antibodies, which are highly inaccurate, at most 60 % accurate of a food sensitivity. You're gonna see a lot of false negatives and false positives. So the mediator release test is basically measuring 170 different foods and chemicals against your blood.

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so that when you consume that food, it's not, that food bad for you or am I allergic to that food? Is it that I'm not digesting that food properly because of what's happening in what I call GI North, Insufficiencies with stomach acid, bile salts from the gallbladder or pancreatic enzymes. So now, GI North and GI South. So we're not digesting it and because of that, you're creating an inflammatory response to that specific food. So I'll never forget my first test.

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Josh Dech - CHN (31:29.066)
GI North, I like that.

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Dr. Daryl Gioffre (31:41.633)
Avocado showed up. Avocado is like the most perfect food in the world. It's what I call God's butter. It has all the macros that you need. But it wasn't right for me in that moment because I wasn't digesting it. And because of that, as that particle, which was not a tiny little avocado particle like it should have been in my gut microbiome that the body can take in for fuel, my immune system's like, that looks like a Dr. Darrell avocado, but no, that's not. I'm being tricked.

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That's non-self, that's a pathogen and it attacks that food because it sees it as non-self and in that attack mode, that creates an inflammatory response that's gonna create dysbiosis, gonna kill off the good guys and more leaky gut. So the Meteor release test is amazing, has a 94.5 % sensitivity, which means if you have a sensitivity to that food, it's there. And a 91.7 % specificity, which means if I'm not, if dairy doesn't show up, it means

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most likely I'm not having a sensitivity to dairy. So I love it because we know that if that food's there in a yellow or a red bar, we gotta avoid that food for three or six months. If it's a green bar, hey, now I can eat that food. So now we're ditching keto, we're ditching vegetarian, vegan, we're ditching, which is not the healthiest diet anyway, we're ditching whatever diet is Mediterranean, it's not about the diet, it's about the right bio.

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individualistic diet for yourself. It's basically what your body needs in that moment that's not going to create inflammation when you eat that food. And basically

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Josh Dech - CHN (33:08.8)
I want to put a pause. I'm just going to I want to interrupt you here, Darryl, because the first thing that's coming to my mind is why? Because it's bullshit. It's like, it's food. I should be able to eat it. And if it was a thousand years ago, we'd all be dead because there's so many things I can't eat that we didn't have an M.R.T. Why do we even need to test to know what we're able to eat or not?

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Dr. Daryl Gioffre (33:17.773)
Yeah.

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Dr. Daryl Gioffre (33:25.644)
Because, because, because a thousand years ago, we weren't toxic like we are now. There was actually nutrients in the soil. We were actually foraging. We were hunting. We were moving our body. We weren't stuck in a desk like our kids are for eight hours. We weren't killed with the stress, the EMFs, the phones. mean, literally we could go on and on and on about the exposure that we have. It's incredible that we make it past 20 years in today's day and age. And that just shows how resilient the human body is.

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how life force, how God can heal us, right? The power made the body heals the body. So the reality is that you don't need to do all these testing, but don't let yourself get to the point. Like, I'm so blessed that now I have a seven and 10 year old that were raised up in the lifestyle that I know is a healthy lifestyle. Now here's the thing, they're still under attack out there because you could do all the right things. this is probably the biggest thing I'm gonna say today is that I get patients coming to me every day, say, Dr. Darrell, I'm eating all the right foods, they're organic.

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I'm exercising, so I'm moving my body. I'm eating the top big five supplements that we know everybody is deficient in. Heck, I'm meditating. I'm praying. I'm doing all these things and my gut's still a mess. Yeah, that's the problem. It's because your gut is the first line of defense and it's been under attack since the, not since the moment you've been born, since before you've been born. There was a study by the EWG, the Environmental Working Group, and it was basically studying the placentas of babies that were born. They found,

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Josh Dech - CHN (34:53.013)
Mm.

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Dr. Daryl Gioffre (34:53.614)
270 different toxins in the blood of the baby that was just born. that, 180 of those toxins cause cancer. So I wonder how my cousin was born, and I get that all the time, like how was my cousin born and had cancer when she was born? Because we are so toxic. And it's the toxic exposure that destroys the gut. So we didn't have that a million years ago or even 250 years ago. So times are different. So we have to be more proactive. We have to have EMF blockers in our house.

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need to eat organic foods, we need to demand organic. I know it's more expensive, so that's why I go to my local farmer's market. I find friends that raise chickens here in Florida that we can get, you know, grass-finished eggs, because I hear this all the time. Again, came up on this call, I'm eating healthy eggs. The egg-yo came up on his food sensitivity test today, and he's like, no wonder why I feel awful after eating eggs, but I'm going, I'm eating organic eggs. I'm like, but what also came up on your test was soy, and if you go to a store,

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Josh Dech - CHN (35:45.034)
Hmm.

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Dr. Daryl Gioffre (35:52.505)
There's no way you are finding a grass-fed, grass-finished egg. It could be organic, it could be pasture-raised, but I promise you, it's fed corn and soy. Every single egg, so, right, right, right, right. So like, it's not about having this crazy diet where you have to like avoid every food in the world, but it's about identifying now in the moment why you're feeling this way. If you have a symptom, that's not normal. We weren't meant to have symptoms. Symptoms are your warning sign. I mentioned the toothache before.

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Josh Dech - CHN (35:56.628)
No.

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Josh Dech - CHN (36:01.588)
Yeah, yeah, they're not eating bugs, not eating beetles, they're not eating stuff they normally eat.

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Dr. Daryl Gioffre (36:21.996)
When you get a toothache, the day before you have that toothache, was that tooth fine? You didn't have any symptoms. There was no pain in that tooth. But no, dental research shows it takes at least 15 months of decay in that oral microbiome to that tooth and to that gum to trigger the actual toothache. The symptom is the warning sign, everybody. The question is, is are you paying attention to that? the other thing is that we want to get to the point so that we're not getting those symptoms in our body. So that's what being proactive is.

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I test my children's gut, they're seven and 10, they don't have any symptoms. They eat healthy. We're not like some crazy parents that don't let them, if they're going to a kid's party, let them have the cupcake, right? But when they're home, we keep it clean, we keep it healthy. They take supplements. But I did a stool test on both of my kids about eight months ago. Both of them had a parasite in their gut. It's crazy. No symptoms. That's not normal.

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Josh Dech - CHN (37:09.45)
Hmm. Is that the second test that you do? You said you do two different tests. You do the MRT is the first one to identify exposures and problems. What's the second test you like to do that you think everyone should be doing?

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Dr. Daryl Gioffre (37:21.294)
The second test is called a GI map test. It's a DNA stool sample test. And basically what we're looking at is every sort of pathogen that could be affecting you in your gut, which we call stealth gut infections. Stealth gut infections means they're in your gut, they're affecting you, but you don't know they're there. Just like a stealth fighter above us. Like there could be a stealth fighter up there. You can't see it. You can't hear it. You could be dead in a second because it dropped the bomb on you. Right? So, it's looking at parasites. It's looking at inflammatory bacteria.

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the strong ones like C. diff and salmonella and E. coli and other forms of bacteria like Pseudomonas and Citrobacteria and Staph and Strep and things like that. So we're looking at all of those. We're looking at fungal strains such as Candida, which is yeast. We're looking at H. pylori, which is a very interesting topic of conversation related to acid reflux and other sorts of inflammatory, you know.

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active viruses and things like that. We're looking at the healthy side of the microbiome. So we're looking at what's called your keystone bacteria, which are your probiotics. Acromansia, I mean can't tell you how many patients we see acromansia completely wiped out. It's one of the most important gut bacterias that we have. Well why, the question I always ask when I see the healthy probiotics, the flowers in your garden that are wiped out, why did the gut become weak in the first place? Well I'm taking a probiotic Dr. Darrell, that's good, I get that.

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Alright, but just because you're taking a probiotic doesn't mean that there's not a sniper in your gut taking out your probiotics, right? So when we look at all these inflammatory bacteria and pathogens, those are the snipers, those are the weeds that take out the good guys, right? So we're looking at the bad guys, we're looking at the good guys, and we're looking at the whole digestive process. We're looking at something called a stay adequate, which is a measure of gallbladder function. Are you digesting your fats properly? Well, you don't need stay adequate to know, just look at your poop. Is it floating or is it sinking?

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If it's floating, you probably have a sluggish liver and gallbladder and you need to have more beets and beetroot juice and things like that to kind of help get that bile out. It looks at something called the last taste one. Is that pancreas functioning properly? Is it producing enough of the digestive enzymes you need to break down your food? It looks at the very important marker called calprotectin. Calprotectin is a specific protein released by the neutrophils in your gut, which are your white blood cells, your good guys, and they're there in the presence of inflammation.

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Dr. Daryl Gioffre (39:39.343)
that number should be zero. And by the way, calprotectin is the gold standard for IBS, irritable bowel syndrome, IBD, and even things like colorectal cancer. So that number should be zero. 50 to 167 is moderate inflammation, and once it goes above that, that's outright inflammation. The patient this morning had a number greater than 500, which was horrible. So yeah, it's like a little worrisome for them when they see it, and the first thing I say is listen.

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Yeah, I'm concerned about these numbers, but don't be worried. Like these are all reversible. Here's the good news. You've identified the problem. You spent 25 years of your life on these PPIs and you're just making the problem worse. Now you've identified the root cause. Now you can actually put together the right protocol as far as diet, the right supplements, the right techniques to manage stress, to reverse these things that were causing all these issues and symptoms in the first place. So that's the second test. It's amazing.

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Josh Dech - CHN (40:33.216)
So my question to you then, Daryl, is, and I'll put some preface on this, but the question just to tee it off is do you believe this is what everyone with a gut issue should be doing? And here's why I ask. We are now hundreds of cases of Crohn's and colitis reversed off medication, very reversible conditions. Like they're not these autoimmune genetic random conditions we've been told they are. In fact, the data from the CDC disproves that we can go down that rabbit hole if you'd like. But I used to swear by GI mapping. I was like, this is an amazing tool. It tells us everything.

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And then I started realizing for these really severe, what looks to be either immune mediated or autoimmune conditions where there's massive inflammation, imbalances of the immune system. I used to think that, well, the GI map can tell us everything. But what we've found is that it's a downstream issue. So if I find in a GI map, your bacteria is all screwed up. It doesn't tell me why it's screwed up. The MRT can show me what might be contributing to that. But we're seeing a lot of parasites, which rarely come up on stool tests anyway.

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We're seeing a lot of mold infections, which again, you won't get on stool testing. It's got to be more symptomatic based. can look at blood work or even of course you can do specific testing. We are seeing some clostridia, which again can come up on that, but also an organic acid test. We're seeing a lot of differences or even Candida as a fungus being a primarily small bowel microbe. You don't always see it presenting in the large intestine on a stool sample anyways. So I used to think,

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that everybody needed a GI map and everybody needed food testing. But as we really got down to the niche of Crohn's colitis, even severe IBS, we sort of found them, maybe they're better at month four and six. Once we've got the bulk of the junk removed, the parasites removed, we've got the mold under control, now we can look to fine tune. But I'm interested in why your bacteria got screwed up. Not looking at it right now, but looking at it later to see what's left to clean up. So I'll circle back to my original question.

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Do you believe I'm right or wrong in this? you believe everybody should be doing these regardless? What are your thoughts on that?

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Dr. Daryl Gioffre (42:32.172)
It's a phenomenal question. It really is. And there are so many questions within that. So I want to cover a few of those. Hopefully I can remember all of them. but, there are deficiencies in every test. like we can only use with the best information we have now in this present moment. there are some times I'll do a deeper test. If I really want to go deep, if like, if I suspect like power, cause you're right, parasites love biofilms. They, are cyclical in nature. So sometimes, you, you won't see it. So whenever we start a protocol, we always do biofilm disruption.

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because the parasite could be hiding from the immune system. It could be hiding from us on the test. It doesn't mean it's not there. It doesn't mean that it's not causing damage, but biofilm disruption is something that's so important. Sometimes I'll do biofilm disruption before I even do the test to draw out some of these hidden creatures that are hiding under the surface, like an invisible cloak, to bring it out into the open. If someone's really symptomatic, I'm not gonna do biofilm disruption before a test because that'll throw them over the edge. They're not ready for that yet.

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I definitely agree with you that you gotta have, you gotta take this in steps. You have to kind of manage each patient differently based on what their presentation is, how bad their symptoms are. But to answer your question, does everybody need this test? I think that gut testing needs to be as common as cholesterol testing, as common as blood sugar testing. Yeah, and I'm serious because I've done thousands of these and while it might not be the 100 % be all, it's gonna give us so much information when you look, I had IBS.

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Josh Dech - CHN (43:46.304)
I love that.

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Dr. Daryl Gioffre (43:58.511)
and all these doctors did was maybe eat those things at Tom's. So it's gonna identify things in there. It might not identify everything because it could be hidden. It could not be showing on that specific test. And Candida's a perfect example. Of the GI map, the one thing that I don't like about that test is the Candida aspect of it. I'm not gonna say not like about it. All the other bacteria when you take the stool test, or my son calls the poop test, when it hits oxygen, those bacteria thrive very well. They're not gonna die off.

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Candida is the complete opposite. It's gonna die off the second hits at oxygen. So you can't use it as a definitive test for Candida. There's other markers that we can see. I mean, I have a simple test that you can spit in this glass and the second you wake up and without doing anything, not drinking, not brushing. And if you start to see strands coming down within 15 minutes to an hour, that's a sign of Candida positivity right there. Yeah. And then the common things, if you have white on your tongue, clearly that's a Candida overgrowth. If you're craving sugar,

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Josh Dech - CHN (44:29.728)
Hmm.

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Josh Dech - CHN (44:48.611)
that's interesting. I didn't know that one.

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Dr. Daryl Gioffre (44:56.846)
clearly you're gonna have overgrowth of Candida. Here's by the way, how I know 100 % of people have leaky gut. It's the Candida. So when I'm doing my live blood cell analysis where we take a pinprick of someone's finger, we put that under a microscope and we magnify that, you know, so we can look at it under a HDTV and we're looking at your live blood in real time, I have seen fermentation in Candida in 100 % of every blood supply, blood sample that I've seen. And by the way, I'm talking thousands and thousands and thousands.

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Josh Dech - CHN (45:22.56)
Wow.

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Dr. Daryl Gioffre (45:27.022)
My daughter, Aliyah, she's seven now. When she was born, she was having this kind of like a tear on her left eye and we couldn't figure it out. So of course, you I want to test her live blood and she's three months old. So we go into my office in New York City and my wife's there, she's holding Aliyah and I give the little glucose stick to prick the finger. like, you know, I have an infant one and I give it to my wife, Chessa. I'm like, here, you do it.

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I go, you're the mom. She's like, no, you're the doctor, you do it. I'm like, I'm not doing it, you do it. So we're sitting there arguing for like 15 minutes, who's gonna prick her finger? She falls asleep, I prick her heel, we put her under the microscope, and lo and behold, she's got Candida in her blood. Well, how on earth can that happen to a newborn baby? Well, she was pike breech, which means her head was up and her feet was up, so she was basically like a U. Because of that, we had to have a C-section, and of course, antibiotics were given in the hospital, and we know the whole story based on that. So my point is that,

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Candida, everybody's got it, but when it's there in large amounts, that's bad. So if I don't see any Candida in that stool sample on the report, it doesn't mean that there's not a Candida problem. We have to look at the other symptoms as well, but if I see Candida show up, which I do see, maybe in 20 % of my patients, even in small amounts, that means that that patient has a significant Candida problem. Because for it to survive the oxygen to show up on that test, there had to be a lot of that specific pathogen.

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And if it's in high numbers, then that's a bigger problem. I do believe that everybody needs to test. And I think that it's something that we should do like once a year. We do a comprehensive blood panel every year. I think it's something that everybody should do. I'm not saying you have to do that, but it will uncover something in there possibly that's causing damage, causing destruction, but it hasn't showed up as a symptom yet. My two kids, Braden and Aliyah, were perfect examples. They had a parasite. I put them on a parasite protocol.

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And again, I retested them in four months later, the parasites were gone. So I don't want that to manifest inside there causing more dysbiosis, causing more leaky gut. So somebody that's in the IBS stage that you were talking about, the Crohn stage, that's a serious problem. You have to test that person's gut because what are you gonna do? Yeah, you could clean up the diet, but all right, so eat these specific foods because we know these foods are good for your gut. So they start eating fermented foods, but they have SIBO. I don't need a SIBO test to do that. Most of my patients have SIBO, right?

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Josh Dech - CHN (47:45.428)
Mm-hmm.

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Dr. Daryl Gioffre (47:46.563)
The weeds are overtaken in the garden, there's no room for them in the coal, and they start working their way up into the small intestine, and they don't stop there. So now, you're taking a terrain-based probiotic, like a Clair, and I love Clair Labs' therabiotic, it's a great probiotic. You can take one by pure encapsulations, but the live probiotics are not the probiotic that you wanna take right now. Because of this overgrowth of bacteria, they're gonna start to ferment because they're live bacteria, all that food, and whatever it is, the bacteria in the small intestine.

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It's the same thing with our fermented foods. You start giving that patient fermented foods, which we know are good gut friendly foods that help heal the gut. But if someone has SIBO or CFO, small intestinal bacterial overgrowth or small intestinal fungal overgrowth, you're gonna actually start to ferment that food higher up in the chain by that bad bacteria, because it's in a place it shouldn't be. So again, this is the problems that all these people are doing things.

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that they hear people talking about that normally should be good for people with gut problems, but now they're not getting well, they're getting sicker. It's because you need to know what's going on in that gut. So my whole mantra is test, don't guess. And listen, if there's minimal going on, I'll be the first to give my patient a high five and say, listen, you're doing great. Keep on doing what you're doing. Let's make some changes in your diet, right? These foods you're eating right here are showing up as inflammatory foods. Now we know that. Let's remove those for a few months. Let's get you on the right probiotic. Let's get you on a spore-based probiotic.

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Let's get you on something to heal and seal that gut wall. We have an amazing supplement that has dairy-free colostrum plus an organic collagen peptide. There's different things you can do that cost minimal. Get them on bone broth, right? I mean, you have amino acids in bone broth like proline and glycine that are gonna heal that gut wall and help repair the damaged tissue. There's so many things that you can do, my point, without testing. So I'm always here to keep my patients' budgets in mind. I'm not saying that you have to test. I'm saying if you have the Wherewithal 2 test,

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it's gonna give you more information. The more information we have, the more laser focused we can be at targeting what might be in there that's causing damage, destruction that we didn't know without the testing. But if you don't do the test, there's so many things that we can do to help people with reflux and to help people with bloating and constipation. You don't need a test to do that. Listen, I want people to feel well. You don't have to go all the way down the chain and do everything with us to do that, but there's so many ways to get people to feel better, but it might not be what they need to heal.

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Josh Dech - CHN (50:01.961)
Yeah.

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Josh Dech - CHN (50:09.918)
Yeah, I think that's brilliant. I think it's so important to note that it is so contextual. You get so many people with so many different aspects of illness, you know, and you can run a million and one tests and come up with nothing. You can run a million tests and come up with everything. You can run one test that's very targeted and have all the answers you need based on the context you're running that test in. And that just really highlights the importance of finding a practitioner.

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Dr. Daryl Gioffre (50:30.446)
Yeah, and hormone testing is the perfect example of that. It's like, if you're testing your hormones through blood, it's worthless. 99 % of your hormones are bound to protein. That's like if I want to buy this house, I'm looking through a keyhole to see what I'm buying. You're not seeing it. There's false negatives, false positives. You need to do a saliva hormone test if you're pre-menopause. Then we're looking at the entire menstrual cycle. We're doing 11 checkpoints. So we can really look at what's happening throughout the entire cycle, not just one nanosecond.

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Josh Dech - CHN (50:35.306)
Yeah.

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Dr. Daryl Gioffre (50:58.678)
of a moment where your testosterone could be high or could be low and then you're basing what you're gonna do with that patient based on that. Right. The time of the test will change the hormones, right? So again, that's a perfect example of like, let's test smart. Let's do it the right way if we're gonna do it because so many times patients will go down that rabbit hole and they'll see a million different doctors and they're doing all these different tests but they're not getting to the root cause because of these things we're talking about.

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Josh Dech - CHN (50:58.805)
Mm-hmm.

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Josh Dech - CHN (51:02.494)
Yeah, if you didn't sleep the night before, your blood's gonna be all screwed up anyway, right? 100%.

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Josh Dech - CHN (51:14.431)
Yeah.

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Josh Dech - CHN (51:25.268)
Yeah, I love that.

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Dr. Daryl Gioffre (51:25.42)
And that, I want people to save their money and how do we do that? Like buy...

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really going after this and talking about the right foods to eat at the very, cause you can't supplement your way out of a crap diet, right? So you gotta get the right foods in place. There are a few supplements that everybody needs to take, like get on some magnesium, get on some D3 with K2, take omega-3 fish oil. We need that for our brains. It's responsible for 96,000 preventable deaths, omega-3 deficiency, right? Get on a good probiotic, like just doing that alone, you're gonna see significant changes in your health, but then you can go to the next level if you want.

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Josh Dech - CHN (51:56.929)
And remember guys, you get what you pay for. If you go to the grocery store and buy those garbage Jameson vitamins, it's just expensive pee. So make sure you are buying quality supplementation. Well, let's wrap this up really quick here because I know we only got a few minutes left together, Darryl, and I want to make sure we can give some real tangible takeaways here. I know we covered two broad topics with a lot of root causes here, acid reflux and leaky gut.

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Dr. Daryl Gioffre (52:03.852)
That's right. It's so true.

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Josh Dech - CHN (52:21.098)
Quick wrap up here, know acid reflux is low acid. It can be stress. can be mineral deficiencies, overeating, leaky gut, inflammation, bacterial. We didn't get a chance to cover H. pylori, but perhaps another time. But here's what I want to do. We've covered acid reflux and leaky gut. What are the simple steps, the right nows that somebody can do, someone can take to start healing these things or improving these conditions?

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Dr. Daryl Gioffre (52:46.732)
Love the question. Number one, we gotta stop the poison. So before we talk about what we're gonna put in the body, let's talk about what we're not gonna put into the body. So let's dump those seed oils, which are way more damaging than sugar to the body and to the microbiome. mean, your body will try to get rid of the sugar right away, because it knows it needs to burn it off, because it's bad, but the seed oils have a half-life of seven years. So please, the seed oils and the artificial sweeteners are the two worst.

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Of course like antibiotics, but sometimes you have to do that, right? There's other ways around that. I'm very blessed that my children seven and 10 have never been on an antibiotic because we use things like bioactive silver hydrosol, right? And other things to strengthen the immune system. So it's about avoiding those foods that are going to drive up inflammation in the body. So please go gluten free, right? Let's get off dairy for a few months and just see how you feel, right? Do a 10 day dairy challenge. When you say, I'm not going to do dairy gluten for 10 days.

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I promise you, you're gonna feel so much better, you're gonna wanna keep going, all right? Try to invest in better meat, so it's not just about the quantity of meat. Two to four ounces per meal is like the amount that you don't wanna go above, because then it could start to actually create sugar in your body via gluconeogenesis in the liver, but it's about what the animal that you're eating is eating. So please, do your best to find grass-fed, grass-finished meats and things like that in eggs.

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And of course, the artificial sweetener, as I mentioned before, is a big one because that's gonna destroy your gut microbiome. As far as things we can put into the body, lots of leafy greens, we need more minerals. Yes, you can eat the greens, but I love to drink my greens. I'm a huge fan of green juice. It's the core of what I call a strength eating diet. So I love green juice in green smoothies and green soups. I mentioned bone broth. Bone broth is an incredible gut healer. And again, you're like kind of giving your gut a break because the gut is always working.

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So when you have these things in liquid form, it's going to be easier for you to digest and assimilate those nutrients from those specific things. that's why I'm a big fan of bone broth. I consume it every single day. And as far as specific things you could do for acid reflux, I love local honey with something called propolis. So my voice is a little hoarse right now because I was yelling at my kids soccer game coaching this weekend, but I was using that for my hoarse voice before I came on this podcast. But I got a teaspoon of local honey.

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Dr. Daryl Gioffre (55:02.636)
I got three drops of propolis, is basically a very powerful antibacterial, antifungal, antiseptic, anti-inflammatory, antiviral, and I put that in there and I just mix that and I just basically, you do three teaspoons a day. And what that's gonna do is gonna soothe and calm the throat, the mouth, the esophagus, the stomach. So it's very healing. The honey will soothe, the propolis will heal ulcers. So many different amazing studies on that.

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something like a throat coat tea, you can buy the packs. They're like very inexpensive by traditional medicinals or by yogi. They have a throat coat tea as well. That's consistent of slippery elm. So they have slippery elm and things like licorice root, which are again, upper GI soothing and healing. So I love that. I make my own tea with marshmallow root and cinnamon. So I'll get a bag of marshmallow root from Star West Botanicals. By the way, I have no connection to any of these companies guys, but I'll get.

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a bag of marshmallow root and I'll get a bag of cinnamon bark and I'll get three tablespoons of marshmallow. I'll get like a big jar and I'm making my own tea batch. I'll get three tablespoons of marshmallow root and then for every three tablespoons of marshmallow, I'm doing one tablespoon of cinnamon and I'll do three tablespoons of marshmallow, one of cinnamon, three, one, three, one. I'll fill up a whole glass jar and I'll just shake it up and then I'll take one tablespoon of that and I'll put that in eight ounces of water. You just let it sit there for hours. And what I do is I actually get four tablespoons, 32 ounces of water in a big jar.

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I let that sit overnight and then you come the next morning, you're have like this straw yellow color. You just strain it and then you drink that throughout the day. That is very soothing and healing. So there's so many different things you can do to calm and soothe the acid reflux. You can go as far as taking a supplement called BPC 157. You can open up the capsule, put that in an ounce of water, drink that on empty stomach. That will heal ulcers created by acid reflux. Our acid kicking minerals are phenomenal because they're loaded with not only

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the most powerful macrominerals, but they have sodium bicarbonate, which is gonna soothe and calm. So I have my reflux patients do that three times a day in three ounces of water. So again, there's so many different things. I gave you a big list right there. Start with one. Whatever kind of resonated with you, start with one of those and that will be something that's really, really gonna be like your starting point that you can go up from there. I have a great leaky gut protocol. If we have time to talk about that, we can do that as well.

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Josh Dech - CHN (57:14.88)
Yeah.

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Josh Dech - CHN (57:19.692)
yeah, yeah we do. And I want to put a quick pin in something as well. And again guys, find a practitioner specialist like what Darrell's saying, reach out to him. That's great. Individuality in the cases of things like molding, if you've been listening long enough, you've been really paying attention cases like mold, parasites, Crohn's colitis, even some severe IBS. have to watch like bone broth might not be good for you right now, even though it's good for the gut. It's a high histamine food.

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mold parasites especially in the cases of Crohn's colitis or see elevations in an immune pathway called th2 th17 sometimes number 9 But this is where we see a lot of histamines being driven. So it's like your cups already full So if you eat a high histamine food like bone broth avocados cured meats fermented foods for the probiotics It might cause you a problem right now, but that comes back to what Darryl was saying earlier about it's not bad It's good. It's just bad now

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And so individuality is everything. But talking about this leaky gut protocol, you mentioned you guys do something that's really amazing and extremely powerful.

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Dr. Daryl Gioffre (58:22.83)
Yeah, and if you are having high histamine response in MCAS, avoid leftovers, because leftovers are gonna skyrocket your histamine response. So that's something you wanna look out. And when I deal with my mold patients, because I deal with some very sick mold patients, I'm on the board for Christian Medical Ministries with Dr. Alan Groening, one of my dearest friends, and our goal is to help the underprivileged people who are suffering with SERS, which is biotoxin illness from mold and other biotoxins. It stands for chronic inflammatory response syndrome, which nearly killed me four years ago.

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Josh Dech - CHN (58:27.946)
Yes.

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Dr. Daryl Gioffre (58:51.822)
What we'll do is we'll put a lot of our patients in the beginning on a carnivore diet. Now, I'm the last guy who ever would have talked about the carnivore diet because there's a lot of downside to the carnivore diet, especially with gut dysfunction, but it's also very low histamine. And what we find is that these patients who are highly reactive to everything, like they can't eat anything, like they seem to do okay with like a carnivore diet for a few weeks or a few months. Like you have to get the minerals in because that's one of the biggest things. It's going to cause a lot of disruption.

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to your point, like you have to adapt and you gotta see like what's going on and you have to, it's not one size fits all is what I'm saying, right? And that's what we need to do as practitioners. We have to really kinda work with our patients one on one to give them the tools that they need and the advice that they need in that moment in time, cause it's ever changing. All right, so the leaky gut protocol is amazing. We know that antibiotics will destroy your gut for at least two years. So this is also a post antibiotic protocol.

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When I first created this it was actually a candida protocol because this works amazingly well for fungus mold and for candida in the gut So what you're gonna do and you will need two supplements for this The first supplement is called the ingredient is called bioactive silver hydrosol The company name would be either sovereign silver or Argentin 23 Argentin 23 is twice the price. It's stronger 23 parts per million compared to 10 parts per million So let's just for the sake of it. Let's use sovereign silver. It's less expensive

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Josh Dech - CHN (59:55.946)
Mm.

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Dr. Daryl Gioffre (01:00:17.71)
So you're get a 32 ounce bottle of Sovereign Silver and you're gonna get a 32 ounce bottle of liquid aloe vera. I like George's aloe just because it's very neutral, it tastes like water. So what you're gonna do is you're gonna take one tablespoon of the Sovereign Silver, one tablespoon of the aloe vera, mix it together, drink that on an empty stomach three times a day for a minimum two weeks. You gotta do it for two weeks. What does an empty stomach classify as?

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You need at least 30 minutes clearance time before a meal, at least 90 minutes clearance time after a meal. Okay? The aloe is very soothing to the gut. It's very calming to the gut. It helps heal leaky gut. It helps coat the stomach. So it does a lot of amazing things. Plus it also protects the silver as it navigates through the gut. And once it's in the microbiome past the acid in the bile, it opens that up. Now the bioactive silver is amazing because it's a selective antioxidant.

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It's a very powerful antiviral, antifungal, antibacterial. It's an immunomodulator, so it's gonna boost immune function and it's very gentle. It will eradicate these harmful pathogens in your gut. It will help heal that gut wall, but it does it in a very gentle way. So this is a very good thing that I do with a lot of my patients before I even put them on a protocol because it's gonna help them heal and seal the gut wall and it's gonna help start to strengthen their gut and get rid of some of these pathogens that we want to get rid of, but not.

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activating some form of Hertz reaction in them. So you do it for two weeks. I also like to add in...

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Josh Dech - CHN (01:01:43.968)
Can you overdo it though? Can you overdo it for like two months or two years? Drink too much colloidal silver, kill off too much good guys?

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Dr. Daryl Gioffre (01:01:50.793)
it's, and again, let's be careful because I don't want anyone using colloidal silver for this. It's a much larger molecule. So bioactive silver is the only ingredient I would use with this. yes, you can overdo everything. Of course. if you eradicate, eradicate, eradicate, even in a gentle way, too much time of doing that can actually have a downside. So I think the most I've ever done with a patient was eight weeks. Like everything you want to, if you think they need more of that, I stopped them and then I focused on some other things. I can always bring them back to that, but usually I don't have to like that's how good this protocol works.

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People who are the most symptomatic, the most dysbiotic, they can usually handle this. If you find that you're having trouble or you're very symptomatic or you're very activated by like the littlest things, I wouldn't use a tablespoon, I would start with a teaspoon of each. So again, less is more sometimes. I always like to do a spore-based probiotic when I do this. I'll do one capsule of a mega sporebiotic or a Just Thrive or whatever one you like to use.

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I'll do that for a week then I'll add a second one and I'd like to do that at my largest meal of the day. We have an amazing product called Gut Punch which again helps to soothe the gut line. So it's really about how many things you want to add but minimal just doing the silver and the aloe it's so powerful and it goes a long way. So I love it and it works really really well and for anybody who's been on an antibiotic, red, everybody or most people, this is something that you

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definitely need to do because it'll help heal that gut wall. And again, we've measured this with zonulin markers. It's incredible the changes in just two weeks, like how much that zonulin marker has gone down.

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Josh Dech - CHN (01:03:27.732)
That's amazing. And it's measured, you've tested, you've not guessed it. And so you guys know what's working, what's not. I love that. Well, Darryl.

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Dr. Daryl Gioffre (01:03:33.108)
Hey

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Josh Dech - CHN (01:03:36.321)
I this is a really cool topic of conversation. mean, like said, I haven't covered acid reflux in probably 150 or more episodes, maybe 200 episodes. So we only covered it once. I'm glad we had a chance to get into here, talk about acid reflux, leaky gut. It's a broad topic, but someone's listening now to like, man, I thought Josh knew some stuff. Turns out he's a dumb dumb. I want to talk to Darryl. High five.

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Dr. Daryl Gioffre (01:03:56.815)
I learned some stuff from you today. What are you talking about? I think, yeah, high five. We gotta rip a little bit more on this. It's fun, but on the flip side, is, reflux is real. I lost my dad to esophageal cancer and that's why I became a gut specialist because I had to and I'll never forget for years. I'm like, what was that dry hacking cough? Why did no one ever notice that? You know, so.

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Josh Dech - CHN (01:04:03.124)
Yeah, I look like a...

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Josh Dech - CHN (01:04:08.212)
Very.

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Dr. Daryl Gioffre (01:04:20.874)
if you have reflux out there, this is not something, I'm not saying this is scary, like you gotta get on top of this and just start somewhere. You can start with just one thing, but there are ways to get off those PPIs, there are ways to reverse that, there are ways to live in your freedom again.

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you this is what drives me every single day. And I had it as well. And I know people that from me experiencing horrific reflux when mold hit me, it's awful. The symptoms that you have and you can become hopeless because you see so many doctors and you see so many different, you know, practitioners and you know, they're just throwing things and hoping it sticks and it doesn't. So we've, we figure out ways to kind of get to the root cause. And that was kind of my vow to my dad. That was my last words, you know,

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I'm gonna do anything I can to help as many people stop suffering from this and you he died and that's my mission every day. So I'm so grateful for you, for your podcast and for what you do and man, your wealth of information is incredible. I mean, you impress me. And when I say I learned a lot from you, I learned so much from you and you're just amazing at what you do and you've helped so many people and I just wanna say thank you for being a warrior out there. And yeah, we will get into those other things because I go hardcore to it, going after the things that we need to go after.

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Josh Dech - CHN (01:05:17.856)
Thank you.

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Josh Dech - CHN (01:05:26.442)
Thank you.

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Dr. Daryl Gioffre (01:05:33.232)
in that world. You mentioned a few, then we don't have to talk about it now, but thank you for being a brave warrior. We need more people like you and I just appreciate you for that.

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Josh Dech - CHN (01:05:41.473)
Man, what a legend. And it's so interesting that there's so many of us in this space who are constantly fighting the uphill battle of the multi-trillion dollar pharma machine. there are people who are suffering from diseases who will defend pharma to the death, even though Pfizer's been in business for what, 150 years and has yet to cure a single disease? So.

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It's really interesting when we start looking at how these things work. I think, you know, guys like us doing our job, being steadfast against the haters and helping the people that we can is what's going to make the difference in this world. And I commend you for it. I think you've done a great job moving from the typical standardized, what everybody says to do to carving your own path, your own experience. And if somebody is really resonating with this right now, Darryl, they're like, I got it. I got to get to know him. I got to reach out. Where they going to do that? How can they find you?

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Dr. Daryl Gioffre (01:06:26.956)
thank you. They can go to my website is Get Off Your Acid, ACID.com. I gotta say that one slowly. And then on Instagram, if anyone wants to do any gut testing, they can just DM us in Instagram or which is at Dr. Darrell Joffrey, D-A-R-Y-L-G-I-O-F-F-R-E. That's kind of like more of where I talk about all these things we're talking about today. The other Instagram is at Get Off Your Acid and that's we have a whole supplement side of our brand that of supplements to treat acid reflux and you know, like.

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People love their coffee, so it's a product you can add in your coffee that neutralizes all the acids, so now you can get the upside of the coffee minus the downside. So we have really cool things like that to help people live their life. I want people to live their life, you know? So that's where you can find me, and yeah, any questions, I answer all my DMs, so please feel free to reach out. I love to help anybody in any way that I can, so we're here for you in any way that you need.

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Josh Dech - CHN (01:07:16.768)
I commend you for being on top of your DMs, man. I get 100 messages a day and I try, but it is, it's a full-time job.

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Dr. Daryl Gioffre (01:07:20.206)
It's hard, it's so hard. And I miss a bunch, but I do the best that I can. And I have a team as well, but I want to be the one to go in there and answer it because the things that they're asking are things that we know. That's why I just hired my first coach after like a thousand years. My team was on me for like, gotta get coaches, I wouldn't do it because I have a high standard for what I do. But I also have to learn to let go and not be so hard and like...

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Josh Dech - CHN (01:07:43.861)
Yeah.

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Dr. Daryl Gioffre (01:07:49.882)
let go and let God as they say and I'm finally doing that now and it's been a blessing because it's freeing me up to do more of the things that I need to do in my life and I don't want to say live in balance because I don't think living in balance is possible but finding my rhythm in life I think we can all find our rhythm of being healthy and that's what I'm doing right now you know and for years I was the shoemaker with no shoes so life teaches you lots of lessons and it's how we adapt to those lessons and learn from them and help other people learn from them as well.

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Josh Dech - CHN (01:08:03.424)
Hmm.

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Josh Dech - CHN (01:08:08.82)
Love that.

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Josh Dech - CHN (01:08:18.546)
Amazing well there I'm gonna put all this stuff in the show notes all the links all the websites all the everything's Appreciate you being here. Love what you're doing I think you got a really good head on your shoulders some really interesting ideas that have actually are Reshaping some things I'm currently working on so I'm gonna take some of these make some modifications to my own protocols And I appreciate you being here man. I look forward to chatting with you again soon